Publications by authors named "Eleonora Kartsaki"
Int J Mol Med
February 2006
Article Synopsis
- Researchers investigated late-onset Huntington's disease (HD) families in Crete, studying their genetic roots and comparing them to typical HD families.
- The study analyzed chromosomes from 33 late-onset HD individuals and found a stable CAG repeat expansion that didn’t show patterns of anticipation or juvenile cases commonly seen in typical HD.
- A shared haplotype among late-onset families traced back to a common ancestor approximately 1000 years ago, indicating that the disease's mutation has evolved slowly over time, possibly influenced by genetic factors.
