Publications by authors named "Eleonora Horvath"
Article Synopsis
- Various US-based risk stratification systems for thyroid nodules are used globally, but inconsistent definitions and malignancy ratings create confusion and complicate comparisons between studies.
- Interobserver variability in identifying ultrasound characteristics also hinders the consistent application of these systems.
- In 2018, an international group of 19 experts formed the International Thyroid Nodule Ultrasound Working Group to develop the International Thyroid Imaging Reporting and Data System (I-TIRADS), starting with a lexicon and atlas of ultrasound descriptors for thyroid nodules.
An important side effect of radioactive iodine (RAI) therapy in patients treated for papillary thyroid cancer (PTC) is chronic sialadenitis. Neck ultrasonography (US) easily recognizes radioiodine-induced salivary gland abnormalities. The objectives of this study were to determine the prevalence of US-detected sialadenitis caused by RAI and to identify the risk factors associated with this damage.
View Article and Find Full Text PDFAlthough most thyroid nodules with indeterminate cytology are benign, in most of the world, surgery remains as the most frequent diagnostic approach. We have previously reported a 10-gene thyroid genetic classifier, which accurately predicts benign thyroid nodules. The assay is a prototype diagnostic kit suitable for reference laboratory testing and could potentially avoid unnecessary diagnostic surgery in patients with indeterminate thyroid cytology.
View Article and Find Full Text PDFObjectives: To determine ultrasound (US) and clinical findings of thyroid microcalcifications in the absence of a nodule and their association with the risk of malignancy.
Methods: The Institutional Review Board approved a 5-year retrospective study. Twenty-one patients with clustered or scattered thyroid microcalcifications in the absence of nodules on US images who underwent fine-needle aspiration biopsies (FNABs) were included.
Background: In most of the world, diagnostic surgery remains the most frequent approach for indeterminate thyroid cytology. Although several molecular tests are available for testing in centralized commercial laboratories in the United States, there are no available kits for local laboratory testing. The aim of this study was to develop a prototype in vitro diagnostic (IVD) gene classifier for the further characterization of nodules with an indeterminate thyroid cytology.
View Article and Find Full Text PDFObjective: To assess performance of TIRADS classification on a prospective surgical cohort, demonstrating its clinical usefulness.
Methods: Between June 2009 and October 2012, patients assessed with pre-operative ultrasound (US) were included in this IRB-approved study. Nodules were categorised according to our previously described TIRADS classification.
Objective: The purpose of this study was to assess the parallel artery and vein sign at color Doppler breast ultrasound as a predictor of the benign nature of breast masses.
Subjects And Methods: A prospective study was performed to identify evidence of a parallel artery and vein in breast lesions consecutively biopsied with a 14-gauge needle under ultrasound guidance. Sensitivity, specificity, positive and negative predictive values, likelihood ratios, and 95% CIs for the parallel artery and vein sign were calculated.
Context: There is a high prevalence of thyroid nodules on ultrasonographic (US) examination. However, most of them are benign. US criteria may help to decide cost-effective management.
View Article and Find Full Text PDFBackground: Retroareolar cysts present in female adolescents with palpable subareolar masses that can have concomitant inflammatory changes. The purpose of this study was to report our cases of retroareolar cysts and thus to contribute to a better knowledge and understanding of this entity.
Methods: Forty-six girls were diagnosed with retroareolar cysts between December 2000 and July 2002.