Publications by authors named "Eleonora D 'Orsi"

Objectives: As the global dementia crisis intensifies, especially in low-and middle-income countries (LMICs), there is a pressing need for comprehensive prevalence data across diverse regions, including Brazil, where studies have been predominantly limited to affluent urban centers. This study aimed to conduct an expert consensus to determine the prevalence of all-cause dementia in Brazil, considering various age groups, sexes, and geographical areas.

Methods: A Delphi consensus process with clinical and academic experts from across Brazil was conducted to provide dementia prevalence estimates in people aged ≥ 60 years living throughout Brazil for 2019.

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Objective: To describe the epidemiological profile and analyze the temporal trend of deaths due to Parkinson's disease among the elderly in Brazil from 2002 to 2021.

Methods: Descriptive and temporal trend study using data from the Mortality Information System. Annual percent change (APC) and 95% confidence intervals (95% CI) were estimated using the Prais-Winsten regression model.

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Background: The population is aging rapidly worldwide, impacting public health, with countries in the Global South, such as Brazil, aging faster than developed nations. The 24-hour movement behavior is crucial for healthy aging, but its relationship with the neighborhood built environment is underresearched, especially for older adults. The EpiMove Study uses accelerometers and GPS to investigate the relationships between 24-hour movement behavior, community mobility and the neighborhood built environment for healthy aging in older Brazilian adults.

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Article Synopsis
  • * It involved 289 older adults, predominantly females aged 70-79, and found that those with ongoing hearing impairment were 181% more likely to experience falls compared to those without.
  • * The findings underscore the importance of auditory rehabilitation and highlight the need for a comprehensive approach to prevent falls by addressing both hearing health and fall risk factors in older adults.
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Objectives: This study aimed to investigate the prevalence of dementia among older adults from Florianópolis, in the Southern Region of Brazil.

Methods: Data were originally drawn from the Epifloripa Aging Cohort Study, a representative and community-based survey designed to evaluate older people's health. This cross-sectional study was conducted in two phases: the community-screening phase, in which the Mini-Mental State Examination and a multifunctional scale were administered to older subjects and close informants, respectively; and the hospital-diagnosis phase, when the Cambridge Examination and the National Institute on Aging criteria were used.

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  • This study investigates how perceived neighborhood characteristics affect blood pressure in older adults, focusing on the role of walking as a mediator.
  • Data from the EpiFloripa Aging Cohort Study revealed that older adults with better infrastructure, safety, and overall neighborhood perceptions are less likely to report hypertension.
  • Results indicate that promoting safe environments for physical activity could be crucial for preventing and managing hypertension among older adults.
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  • Poststroke cognitive impairment is common, but the exact changes in cognitive function following a first stroke compared to pre-stroke levels are not fully understood.
  • The study aimed to track cognitive performance over time in stroke survivors versus individuals without strokes, using data from 14 international cohorts of older adults.
  • Results showed that incident stroke led to a significant immediate drop in overall cognitive skills and accelerated decline in cognitive abilities over time.
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  • A study involving 7,801 older adults examined the connection between fruit and vegetable consumption and the development of depression, finding that higher fruit intake was linked to a lower risk of depression.
  • Over a follow-up period of 3 to 9 years, 21% of participants developed depression, with fruit intake showing a significant protective effect, while vegetable intake did not show a notable association.
  • The authors noted limitations due to varied measurement methods and the relatively modest sample size, suggesting further research is needed on fruit and vegetable consumption in larger, more standardized studies among older adults in low- and middle-income countries.
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Introduction: The COVID-19 pandemic has become a significant health crisis, marked by high mortality rates on a global scale, with mortality from the disease being notably concentrated among the elderly due to various factors.

Objective: This study aims to investigate the biological and non-biological factors associated with COVID-19 mortality rates among the elderly worldwide.

Methods: The following databases will be consulted: PubMed, Scopus, EMBASE, Web of Science and ScienceDirect.

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Objective: To evaluate the direct, indirect, and total prospective effects of serum concentrations of 25-hydroxycholecalciferol (25[OH]D) on depressive symptoms in older adults.

Methods: Data from the second (2013-2015) and third (2017-2019) waves of the EpiFloripa Aging Cohort Study (= 60 years) were analyzed. Depressive symptoms were assessed with the 15-item Geriatric Depression Scale.

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Knowledge of how the different types of sedentary behaviors (SB) are associated with functional limitations can guide professionals who work with older adults on better recommendations about the amount of daily time that should be encouraged in each type of SB. The objective was to estimate the associations between two SB typologies (SB television [TV] and SB computer/internet) and the presence of handgrip strength, lower limb strength, gait speed, and balance limitations in Brazilian community-dwelling older adults. This is a cross-sectional study with 1,298 community-dwelling older adults (≥60 years).

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Objective: To describe the process and epidemiological implications of georeferencing in EpiFloripa Aging samples (2009-2019).

Method: The EpiFloripa Aging Cohort Study sought to investigate and monitor the living and health conditions of the older adult population (≥ 60) of Florianópolis in three study waves (2009/2010, 2013/2014, 2017/2019). With an automatic geocoding tool, the residential addresses were spatialized, allowing to investigate the effect of the georeferencing sample losses regarding 19 variables, evaluated in the three waves.

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Background: Five modifiable risk factors are associated with cardiovascular disease and death from any cause. Studies using individual-level data to evaluate the regional and sex-specific prevalence of the risk factors and their effect on these outcomes are lacking.

Methods: We pooled and harmonized individual-level data from 112 cohort studies conducted in 34 countries and 8 geographic regions participating in the Global Cardiovascular Risk Consortium.

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Article Synopsis
  • The study explored how Walk Score, which measures neighborhood walkability, correlates with older adults' commuting habits, physical activity levels, and screen time.
  • It used georeferenced addresses and various questionnaires to assess walking, physical activity, and screen time among participants.
  • Findings suggested that older adults in more walkable areas were more likely to walk for commuting and engage in physical activity, but also tended to spend more time in front of screens.
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Objective: To estimate the association between negative self-perception of hearing and depression in older adults in Southern Brazil.

Methods: This is a cross-sectional study conducted with data from the third wave of the EpiFloripa Idoso 2017/19 study, a population-based cohort of older adults (60+). A total of 1,335 older adults participated in this wave.

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This study aimed to investigate the association between self-reported hearing loss and cognitive impairment in older adults in a city in Southern Brazil. In this cross-sectional, population-based cohort study of older adults, data were collected in the third wave of the EpiFloripa Aging study (2017/2019), which had been performed since 2009 in the city of Florianópolis, Santa Catarina State. Cognitive impairment was the dependent variable analyzed by the Mini-Mental State Examination (MMSE), and self-reported hearing loss, which was included in the cohort only in the last wave, was the main exposure variable.

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Background: The association between obesity and depressive symptoms has been described in the literature, but there is a scarcity of longitudinal data. This study aimed to verify the association between body mass index (BMI) and waist circumference and the incidence of depressive symptoms over a 10-year follow-up in a cohort of older adults.

Methods: Data from the first (2009-2010), second (2013-2014), and third (2017-2019) waves of the EpiFloripa Aging Cohort Study were used.

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The identification of factors associated with 25-hydroxycholecalciferol (25(OH)D) concentration can help suggest more specific interventions for older adults. In this cross-sectional study of older adults from southern Brazil, we hypothesized that some sociodemographic, behavioral, and health factors positively or negatively influence the 25(OH)D concentration in this population. This analysis was performed using data from the second wave of the EpiFloripa Aging Cohort Study (2013-2015).

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Objective: To estimate the association between vitamin D and the cognitive decline of older adults and evaluate whether this association is mediated by brain-derived neurotrophic factor (BDNF) serum concentration.

Methods: Cross-sectional study nested in a population-based cohort. Of the 604 participants in the complementary examination of the EpiFloripa Study, 576 older adults (60 years or older) were eligible for the study.

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The aim of this study was to investigate the association between healthy food outlet proximity, metabolic syndrome (MS), and two of its components, waist circumference (WC) and systolic blood pressure (SBP), in older adults (63-107 years old, median age 73 years) living in Florianópolis, South Brazil in 2013-2014. This is a cross-sectional analysis of the second wave of the EpiFloripa Aging Cohort Study. Individual-level data on MS, WC, SBP, and socio-demographic and health-related characteristics were collected from face to face interviews.

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This study aims to analyse the association between walkability index and depressive symptoms and cognitive impairment and test the mediating role of moderate-vigorous physical activity (MVPA) in this relationship among older adults from Florianópolis, Brazil. This is cross-sectional research with data from the third wave of the EpiFloripa Aging cohort study, conducted in 2017-2019. Depressive symptoms were assessed using the short version of the Geriatric Depression Scale (GDS), and cognitive impairment, using the Mini-Mental State Examination (MMSE) scales.

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This study aimed to verify the association between the consumption of omega-3-rich (n-3) fish and depressive symptoms in older adults living in Southern Brazil. This is a cross-sectional analysis with data from the second wave of the EpiFloripa Aging cohort study (2013/2014) including 1,130 individuals aged 60 years or older. The presence of depressive symptoms was measured by the 15-items Geriatric Depression Scale (GDS-15), and the consumption of n-3-rich fish by a question of weekly frequency.

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Sedentary activities, such as watching television and using the computer, are frequent conditions in older adults and can be associated with sarcopenia. The objectives of this study were: (a) to establish sedentary behavior (SB) cutoff values for screening probable sarcopenia in community-dwelling older adults and (b) to verify the association between SB and probable sarcopenia according to the established cutoff point. This was a cross-sectional study including 1,165 community residents in Florianopolis/SC.

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This study aims to analyze the association between perceived characteristics of the neighborhood environment and changes in leisure-time physical activity in Brazilian older adults. Longitudinal analysis was performed considering a population-based study carried out in 2009/2010 with follow-up in 2013/2014. Changes in leisure-time physical activity, obtained with the International Physical Activity Questionnaire during both waves, were associated with data of environment perception with the Neighborhood Environment Walkability Scale - Abbreviated (baseline only) performing multinomial logistic regression.

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