Publications by authors named "Eleonora Bovi"
Genes (Basel)
October 2024
Article Synopsis
- - ApoE is a glycoprotein critical for lipid transport and metabolism, with the E4 allele being a known risk factor for Alzheimer's disease and potentially other neurological disorders like Parkinson's disease and brain trauma.
- - Recent findings suggest that the E4 allele is linked to worse clinical outcomes in various neurological conditions, mainly through its role in processes like amyloid-β accumulation and neuroinflammation.
- - This review aims to summarize the role of ApoE in neurodegenerative diseases and discuss the ethical considerations surrounding genetic testing for APOE variants, emphasizing its clinical significance.
