Publications by authors named "Eleonora Beltrami"
Article Synopsis
- Monogenic autoimmune disorders help researchers understand how the immune system maintains tolerance, with various genetic and environmental factors complicating disease control.
- Advances in genetic testing have improved diagnosis speed, but treatment mainly focuses on symptoms due to a lack of research on these rare diseases.
- Recent studies are exploring the link between microbiota changes and autoimmune disease development, suggesting new potential treatment avenues for monogenic autoimmune conditions.
The interest elicited by the large microbial population colonizing the human gut has ancient origins and has gone through a long evolution during history. However, it is only in the last decades that the introduction of high-throughput technologies has allowed to broaden this research field and to disentangle the numerous implications that gut microbiota has in health and disease. This comprehensive ecosystem, constituted mainly by bacteria but also by fungi, parasites, and viruses, is proven to be involved in several physiological and pathological processes that transcend the intestinal homeostasis and are deeply intertwined with apparently unrelated body systems, such as the immune and the nervous ones.
View Article and Find Full Text PDF