Serum Malondialdehyde Levels in Hypertensive Patients: A Non-invasive Marker of Oxidative Stress. A Systematic Review and Meta-analysis.

Introduction: Previous analyses have reported a higher malondialdehyde (MDA) serum level in hypertensive patients (HTs) compared to normotensive subjects (NTs).

Aim: We performed a systematic review and meta-analysis of these studies to offer a comprehensive information on this issue.

Methods: The PubMed, EMBASE and Web of Science databases were analysed to locate English-language articles published from January 1, 2000 up to January 1 2021.