Publications by authors named "Eleni V Geladari"
Article Synopsis
- Adult-onset Still's disease (AOSD) is a rare inflammatory condition that includes symptoms like daily fevers, joint pain, skin rashes, and spleen enlargement, often requiring tests to rule out blood cancers.
- A case study of a 38-year-old man revealed symptoms such as fatigue, high fever, night sweats, and skin rashes, leading to extensive testing, including CT and PET/CT scans that showed enlarged lymph nodes and high metabolic activity in his spleen and bone marrow.
- Ultimately, biopsies of the lymph node and bone marrow showed signs of hyperreactivity but no cancer, confirming AOSD as a diagnosis of exclusion, particularly when high ferritin levels and systemic symptoms are present
Kidney disease is linked to the development of cardiovascular disorders, further increasing morbidity and mortality in this high-risk population. Thus, early detection of myocardial damage is imperative in order to prevent devastating cardiovascular complications within this patient group. Over the years, cardiac biomarkers have been identified and are now widely used in everyday clinical practice.
View Article and Find Full Text PDFPremature ovarian insufficiency and ovarian aging are complex conditions that affect women's reproductive health and overall well-being. They are both characterized by hypergonadotropic hypogonadism and infertility, and together affect about 1 in 100 women by the age of 40. This review explores the influence of environmental factors on the development and progression of premature ovarian insufficiency and ovarian aging.
View Article and Find Full Text PDFWorldwide, diabetes mellitus (DM) represents a major public-health problem due to its increasing prevalence in tandem with the rising trend of obesity. However, climate change, with its associated negative health effects, also constitutes a worrisome problem. Patients with DM are experiencing more visits to emergency departments, hospitalizations, morbidity and mortality during heat waves at ever-increasing numbers.
View Article and Find Full Text PDFObjective: Irisin is a recently discovered myokine proposed to increase thermogenesis-related energy expenditure and improve metabolism. We aimed to comparatively evaluate serum irisin levels in patients with biopsy-proven nonalcoholic fatty liver disease (NAFLD) vs. controls and study their association with disease severity.
View Article and Find Full Text PDFCirculating irisin in relation to insulin resistance and the metabolic syndrome.
J Clin Endocrinol Metab
December 2013
Context: Irisin, a recently identified hormone, has been proposed to regulate energy homeostasis and obesity in mice. Whether irisin levels are associated with risk of the metabolic syndrome (MetS), cardiometabolic variables, and cardiovascular disease (CVD) risk in humans remains unknown.
Objective: Our objective was to assess the associations between baseline serum irisin levels and MetS, cardiometabolic variables, and CVD risk.