Publications by authors named "Eleni Pergantou"
Article Synopsis
- Congenital heart disease (CHD) in neonates is linked to coagulation issues that increase morbidity and mortality, with a diverse population making consistent hemostatic patterns hard to identify.
- A study compared hemostatic profiles of 20 neonates with CHD to 18 healthy controls, revealing prolonged prothrombin time and decreased Factor VII in the CHD group, while Factors VIII, von Willebrand factor, and ristocetin cofactor activity were elevated.
- Though ADAMTS-13 levels were lower in CHD patients, this difference wasn't statistically significant, suggesting that while there is a moderately impaired coagulation profile, there's notable variability and heightened thrombogenicity in infants with CHD that needs to be addressed.
Neonatal sepsis is a life-threatening condition associated with significant morbidity and mortality. Sepsis-induced coagulopathy is a well-recognized entity, signifying the strong cross-talk between inflammation and coagulation. The aim of the present study was to compare the coagulation profile between the acute phase of sepsis and recovery in term and preterm neonates.
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