Publications by authors named "Eleni G Jaswa"
Article Synopsis
- The study investigates the impact of maternal COVID-19 infection during pregnancy on the neurodevelopmental outcomes of children at 12, 18, and 24 months of age.
- It utilizes data from the ASPIRE trial, which involved a diverse cohort of over 2,000 pregnant individuals from all states and Puerto Rico, who were enrolled remotely during the pandemic.
- Results show that children exposed to maternal COVID-19 had a higher prevalence of abnormal developmental scores compared to unexposed children, particularly at 12 months, indicating a potential link between the infection and developmental delays.
Background And Objectives: Polycystic ovary syndrome (PCOS) is a common reproductive disorder associated with an adverse cardiometabolic profile early in life. Increasing evidence links cardiovascular risk factors, such as diabetes and hypertension, to accelerated cognitive aging. However, less is known about PCOS and its relationship to brain health, particularly at midlife.
View Article and Find Full Text PDFArticle Synopsis
- - The study aimed to explore whether mothers' COVID-19 vaccinations during pregnancy impacted their children's developmental scores at ages 12 and 18 months, focusing on neurodevelopmental outcomes.
- - Conducted through a remote prospective cohort study, it involved 2,487 pregnant individuals from all 50 states, who provided data through the Ages and Stages Questionnaire (ASQ-3) assessing various developmental skills.
- - Results indicated similar rates of developmental delays among infants exposed to maternal COVID-19 vaccination compared to those not exposed, with no statistically significant differences in the outcomes after 12 and 18 months.
Article Synopsis
- Extravillous trophoblasts (EVTs) invade the uterus early in pregnancy, remodeling spiral arteries into larger blood vessels, with ongoing debate about the role of immune and stromal cells in this process as pregnancy progresses.
- A multiomics study was conducted to analyze around 500,000 cells and numerous arteries from pregnant individuals, revealing significant changes in maternal immune cell populations as gestational age increases.
- The study developed a model of spiral artery remodeling (SAR) that details how EVT invasion is linked to the regulation of blood vessel growth and immune cell interaction, promoting a safe maternal-fetal environment.
Purpose: To (1) prospectively characterize the incidence of decision regret among women considering planned oocyte cryopreservation (planned OC), comparing those who pursued treatment vs those who did not freeze eggs, and (2) to identify baseline predictors for future decision regret.
Methods: A total of 173 women seen in consultation for planned OC were followed prospectively. Surveys were administered at (1) baseline (< 1 week after initial consultation) and (2) follow-up, 6 months after planned OC among participants who froze eggs or 6 months following consultation in the absence of further communication to pursue treatment.
Objective: To characterize cognitive performance in relation to hormonal and metabolic factors in women with polycystic ovary syndrome (PCOS).
Design: Cross-sectional study.
Setting: Tertiary university center.
Objective: To compare the pregnancy outcomes of lesbian women undergoing donor sperm intrauterine insemination (IUI) with that of heterosexual women undergoing IUI using partner or donor sperm.
Design: Retrospective cohort analysis.
Setting: Two academic fertility practices.
Objective: There are currently various conflicting recommendations for breast cancer screening with mammography in women between ages 40-49. There are no specific guidelines for breast cancer screening in women of this age group prior to assisted reproductive technology (ART) for the treatment of infertility. The purpose of our study was to evaluate outcomes of screening mammography, specifically ordered for the purpose of pre-fertility treatment clearance in women aged 40-49 years old.
View Article and Find Full Text PDFObjective: To evaluate whether physicians' choice of ovarian stimulation protocol is associated with laboratory outcomes.
Design: Retrospective cohort study.
Setting: Single academic center.
Objective(s): To determine whether women with diminished ovarian reserve (DOR) (quantitatively) had lower rates of euploid blastocysts, as a proxy for oocyte quality.
Design: Retrospective cohort study.
Setting: University reproductive health clinic.
Context: Controversy exists regarding if and how body mass index (BMI) impacts antimüllerian hormone (AMH) in women with and without polycystic ovary syndrome (PCOS). Understanding the BMI-AMH relationship has critical implications for clinical interpretation of laboratory values and could illuminate underlying ovarian physiology.
Objective: To test the hypotheses that (1) BMI is associated with reduced AMH in PCOS and ovulatory controls (OVAs) and (2) the reduction in AMH is not accounted for by dilutional effects.