Publications by authors named "Eleni Fragou"
Int J Nephrol
October 2012
Article Synopsis
- Patients with renal failure have a weakened immune system, prompting research into the activation of tumor suppressor genes p53 and RB in their cells.
- PBMCs from healthy individuals, CKD patients, and dialysis patients were cultured under various conditions to measure transcription levels of these genes.
- Results showed that dialysis patients had higher transcription levels than the other groups, suggesting increased cellular senescence and reduced ability for these cells to proliferate in vitro.
