Publications by authors named "Eleni Anastasiadis"

Article Synopsis
  • Male factor infertility affects up to 50% of couples struggling to conceive, prompting research into non-hormonal treatments to enhance sperm production.
  • This study aimed to evaluate the effectiveness of various non-hormonal pharmacological treatments through a systematic review and network meta-analysis of randomized trials.
  • Results showed that clomiphene citrate significantly improved sperm concentration compared to other treatments and was deemed the most effective option among them, although the overall quality of the trials was low.
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Article Synopsis
  • Erectile dysfunction (ED) affects 12-19% of men of reproductive age and is more prevalent among those with male infertility, ranging from 6.7 to 61.6%.
  • While ED is a common issue, it only accounts for 0.4-5% of male infertility cases and is often poorly treated, with current therapies providing only temporary relief without addressing the underlying progression of the condition.
  • The article explores the potential of using intracavernosal injections of platelet-rich plasma (PRP) as a regenerative treatment for ED, which may offer a more effective solution compared to current methods.
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Objectives: We present a summary of penile cancer, its epidemiology, risk factors, and possible clinical presentations. We discuss a range of penile lesions that indicate an underlying penile malignancy. We also consider some nonmalignant penile lesions that may be confused with penile cancer.

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Purpose Of Review: Penile sparing surgery (PSS) is considered the standard of care in penile cancer where appropriate, as preservation of the penis may enable the patient to maintain urinary and sexual function. This review will focus on the latest developments over the past two years.

Recent Findings: In this review, we discuss the latest findings in oncological outcomes in PSS, specifically glansectomy.

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Introduction: Non-urothelial tumours are rare and account for less than 5% of all bladder tumours. Bladder paragangliomas also known as extra-adrenal pheochromocytomas are of the non-urothelial subgroup. We present an unusual case of asymptomatic bladder paraganglioma.

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Since the first partial nephrectomy was first conducted 131 years ago, the procedure has evolved into the gold standard treatment for small renal masses. Over the past decade, with the introduction of minimally invasive surgery, open partial nephrectomy still retains a valuable role in the treatment of complex tumours in challenging clinical situations (e.g.

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Objective: To evaluate the minimum disease burden of prostate cancer at which multiparametric magnetic resonance imaging (MRI) optimally performs.

Methods: Between 2006 and 2008, 64 men underwent multiparametric MRI imaging (index test) followed by template prostate mapping biopsy (reference test). Three radiologists independently reported each quadrant of every prostate on a scale of 1 to 5: highly likely benign, likely benign, equivocal, likely malignant, highly likely malignant (≥3 or ≥4 was considered positive).

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Objectives: To investigate the complication rate within 30 days after transrectal ultrasound-guided biopsy of the prostate in England, and to examine associated risk factors.

Methods: A population-based study was carried out using the English cancer registry linked to administrative hospital data. We included men aged 45 years and older diagnosed with prostate cancer between 2000 and 2008.

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Purpose: To assess the performance of multiparametric magnetic resonance imaging (mp-MRI) in patients with previous negative transrectal ultrasound (TRUS) guided prostate biopsy.

Materials And Methods: Fifty-four patients with at least 1 previous negative TRUS prostate biopsy underwent mp-MRI in the form of T2-weighted, diffusion-weighted, and dynamic contrast-enhanced imaging. This was followed by transperineal template systematic prostate biopsies.

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