Increased brain fractional perfusion in obesity using intravoxel incoherent motion (IVIM) MRI metrics.

Objective: This research seeks to shed light on the associations between brain perfusion, cognitive function, and mental health in individuals with and without obesity.

Methods: In this study, we employed the noninvasive intravoxel incoherent motion (IVIM) magnetic resonance imaging (MRI) technique to examine brain fractional perfusion (FP) in two groups: individuals with obesity (N = 72) and healthy controls (N = 66). Additionally, we investigated potential associations between FP, cognitive function, and depressive symptoms in the participants with and without obesity.