Publications by authors named "Elena Theres Abraham"
Collagen model peptides (CMPs) serve as tools for understanding stability and function of the collagen triple helix and have a potential for biomedical applications. In the past, interstrand cross-linking or conformational preconditioning of proline units through stereoelectronic effects have been utilized in the design of stabilized CMPs. To further study the effects determining collagen triple helix stability we investigated a series of CMPs containing synthetic diproline-mimicking modules (ProMs), which were preorganized in a PPII-helix-type conformation by a functionalizable intrastrand C bridge.
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- The COP1/SPA complex is a crucial repressor of light signaling in plants, with roles in photomorphogenesis, and while COP1 is found in both Arabidopsis and humans, SPA proteins are unique to green plants.
- *In the moss Physcomitrella patens, researchers studied the functions of the two SPA genes, finding knockout mutants exhibited smaller gametophores in light but enhanced growth potential in the dark.
- *The study indicates that while some COP1/SPA interactions and HY5 degradation methods are similar between Arabidopsis and Physcomitrella, the specific roles of SPA proteins have diverged, indicating a more limited function in the moss.