Publications by authors named "Elena Safrygina"
Article Synopsis
- Clear cell renal cell carcinoma (ccRCC) is a severe type of kidney cancer linked to mutations in the VHL gene that affect key transcription factors (HIF1α and HIF2α), making it vital to assess these factors' activation states for better treatment sensitivity.
- A new method called Functional Oncology map (FuncOmap) uses advanced techniques like aiFRET to provide detailed quantification of oncoprotein states, moving beyond just measuring their expression levels.
- FuncOmap enhances the spatial resolution of functional states and helps to differentiate patient responses, improving strategies for personalized treatment in ccRCC.
