Publications by authors named "Elena Roxana Sararu"

Gastroesophageal reflux disease (GERD) is one of the most common gastrointestinal disorders in the world. Two parameters, mean nocturnal baseline impedance (MNBI) and post-reflux swallow-induced peristaltic wave index (PSPW), have been recently proposed to help differentiate GERD phenotypes. Our study aimed to assess whether there is any correlation between the two parameters, while also taking a look at their ability to distinguish between GERD phenotypes.

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Article Synopsis
  • - Gastroesophageal reflux disease (GERD) is a common chronic condition that leads to high treatment costs, with proton pump inhibitors as the first line of therapy.
  • - For patients not responding to initial treatment, further tests like upper gastrointestinal endoscopy or 24-hour esophageal pH monitoring may be needed to diagnose the severity of GERD.
  • - New diagnostic methods, including multichannel intraluminal pH-impedance and parameters like the PSPW index and MNBI, have been developed to improve accuracy and classification of GERD.
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