Synopsis of recent research by authors named "Elena Robeska"
- Recent research by Elena Robeska focuses on understanding the mechanisms of DNA damage and repair, particularly in the context of oxidative stress and radiation therapy, highlighting the crucial roles of specific DNA glycosylases in these processes.
- Robeska's studies demonstrate that targeted nuclear irradiation using proton microbeams not only induces DNA base damage but also triggers a recruitment response from key DNA repair enzymes OGG1 and NTH1, which can improve outcomes in radiation therapy for cancer treatment.
- Additionally, her work reveals the vital role of transcription-coupled nucleotide excision repair (TC-NER) in addressing oxidatively induced DNA damage, suggesting that deficiencies in NER pathways may predispose individuals to neurological and degenerative diseases.
