Publications by authors named "Elena Resino-Foz"
How can we optimize the diagnostic and therapeutic approach to pneumonia? Expert opinion-based recommendations.
Enferm Infecc Microbiol Clin (Engl Ed)
October 2024
Article Synopsis
- - Pneumonia is a common and serious infectious disease, significantly impacting mortality rates and healthcare resources.
- - The OPENIN Group, comprised of specialists in Infectious Diseases and Microbiology, focuses on improving clinical processes related to pneumonia diagnosis and treatment through a review of existing scientific research.
- - The group's initial meeting in October 2023 addressed optimizing pneumonia diagnosis, possibly reducing antibiotic treatment duration, and exploring the use of immunomodulatory strategies like steroids, leading to expert recommendations based on their findings.
This study assessed the molecular epidemiology, resistance mechanisms, and susceptibility profiles of a collection of 150 extensively drug-resistant (XDR) clinical isolates obtained from a 2015 Spanish multicenter study, with a particular focus on resistome analysis in relation to ceftolozane-tazobactam susceptibility. Broth microdilution MICs revealed that nearly all (>95%) of the isolates were nonsusceptible to piperacillin-tazobactam, ceftazidime, cefepime, aztreonam, imipenem, meropenem, and ciprofloxacin. Most of them were also resistant to tobramycin (77%), whereas nonsusceptibility rates were lower for ceftolozane-tazobactam (31%), amikacin (7%), and colistin (2%).
View Article and Find Full Text PDFWe investigated the prognostic role of high MICs for antistaphylococcal agents in patients with methicillin-sensitive Staphylococcus aureus catheter-related bloodstream infection (MSSA CRBSI). We prospectively reviewed 83 episodes from 5 centers in Spain during April 2011-June 2014 that had optimized clinical management and analyzed the relationship between E-test MICs for vancomycin, daptomycin, oxacillin, and linezolid and development of complicated bacteremia by using multivariate analysis. Complicated MSSA CRBSI occurred in 26 (31.
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