Publications by authors named "Elena Ramirez Garcia"
Article Synopsis
- The field of pharmacogenetics is focused on personalizing medical treatments based on individual genetic profiles, but still faces economic, ethical, and institutional challenges for broader implementation.
- A retrospective analysis of anonymized electronic health record data revealed a significant increase in pharmacogenetic testing utilization, with 1,145 tests conducted in one year and a 35% growth over time, particularly in the Oncology department which accounted for over half of the tests.
- The study supports the integration of pharmacogenetic testing into routine clinical practice, highlighting the need for genotype-guided dose adjustments that could enhance patient care.
Background: In April 2020, two independent clinical trials to assess SARS-CoV-2 prophylaxis strategies among health care workers were initiated at our hospital: MeCOVID (melatonin vs placebo) and EPICOS (tenofovir disoproxil/emtricitabine vs hydroxychloroquine vs combination therapy vs placebo).
Objective: This study aimed to evaluate the reasons why health care workers chose to participate in the MeCOVID and EPICOS trials, as well as why they chose one over the other.
Methods: Both trials were offered to health care workers through an internal news bulletin.
Introduction: Invasive aspergillosis is the most important cause of morbidity and mortality in patients with haematological diseases. At present, voriconazole is the first-line treatment for invasive fungal disease. The pharmacokinetic interindividual variability of voriconazole depends on genetic factors.
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