Publications by authors named "Elena Pio"
Article Synopsis
- * TNBC cells of the mesenchymal stem-like subtype utilize cystine to activate the NRF2 transcription factor, enhancing their defense against oxidative stress through a mechanism independent of glutathione production.
- * Four upregulated genes linked to this process serve as negative prognostic markers for TNBC, suggesting that targeting the cystine/NRF2/OSGIN1 pathway could lead to new treatment options for this challenging cancer subtype.
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