Publications by authors named "Elena P Calandre"
Article Synopsis
- * The text discusses both acute treatments (like triptans and neurostimulating devices) and preventative strategies (like flunarizine and vestibular rehabilitation) for managing vestibular migraines.
- * Because vestibular migraine is a relatively new diagnosis, research on effective treatment options is still limited and often has low evidence quality.
Article Synopsis
- Pelvic floor dysfunction includes issues like urinary and fecal incontinence, pelvic organ prolapse, and chronic pelvic pain, affecting women's overall health and quality of life.
- The study compared the health-related quality of life, mental health issues, sleep disturbances, and sexual functioning between women with colorectal-related pelvic floor dysfunction and healthy controls, using various validated questionnaires.
- Results showed that women with pelvic floor dysfunction reported significantly worse mental and physical health, higher levels of depression, anxiety, insomnia, and sexual dysfunction compared to the control group.
Fibromyalgia and migraine frequently coexist. We aimed to compare the burden caused by fibromyalgia (FM), migraine (M) and comorbid fibromyalgia and migraine (FM + M) by assessing psychosocial variables and the use of healthcare resources. A survey was posted to the websites of different patients’ associations.
View Article and Find Full Text PDFThe Probiotic VSL#3 Does Not Seem to Be Efficacious for the Treatment of Gastrointestinal Symptomatology of Patients with Fibromyalgia: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial.
Pharmaceuticals (Basel)
October 2021
Article Synopsis
- Fibromyalgia patients often experience gastrointestinal issues, which can worsen their symptoms, and there's currently no effective treatment for these symptoms.
- A study tested the probiotic VSL#3 against a placebo over 12 weeks to see if it could help improve these gastrointestinal symptoms in fibromyalgia patients.
- Results showed no significant difference between VSL#3 and placebo in relieving symptoms, but those who improved on VSL#3 were better at maintaining their improvements during follow-up, indicating that more research is needed to find effective treatments for this condition.
Objectives: To the scarce information on dietary habits in fibromyalgia (FM), it is added that there are no comparative studies with other rheumatic diseases. The objective of this study was to characterise the dietary habits of patients with FM by comparing, for the first time, with healthy controls (HC) and rheumatoid arthritis (RA).
Methods: This cross-sectional, observational study was based on data obtained from the Dietfibrom project for FM and from the IMID Consortium for RA and HC.
Objectives: To evaluate the patterns of treatment among patients with fibromyalgia (FM) in Spain and to assess patient satisfaction and perceived tolerability of the treatment received.
Methods: An observational, cross-sectional study was conducted in Spain via internet from September 2015 to March 2017. We recorded sociodemographic and clinical information, including treatment satisfaction evaluated using a 10-point numerical rating scale (NRS) and adverse events.
Clustering a large Spanish sample of patients with fibromyalgia using the Fibromyalgia Impact Questionnaire-Revised: differences in clinical outcomes, economic costs, inflammatory markers, and gray matter volumes.
Pain
April 2019
Article Synopsis
- The study aimed to identify clusters of fibromyalgia syndrome (FMS) using the Revised Fibromyalgia Impact Questionnaire (FIQR) and analyze differences in demographics, clinical measures, costs, inflammatory markers, and brain structures among these clusters.
- A large sample of 947 Spanish FMS patients was analyzed through hierarchical cluster analysis and latent profile analysis, which revealed a four-cluster solution that better represented the diversity of FMS symptoms compared to the original severity categories.
- The study found significant differences in clinical outcomes and economic costs among the clusters, as well as variations in inflammatory markers and brain regions linked to pain and executive function, while also creating a free online tool for practical use in clinical settings.
Article Synopsis
- - Gluten-related disorders, such as celiac disease, show both gut and non-gut symptoms, and there's a suggested link to mental health issues like depression and eating disorders.
- - A detailed review analyzed 47 studies (28 in adults, 11 in children) to explore the connection between gluten disorders and mental health, primarily focusing on celiac disease.
- - The findings indicate a clear association between celiac disease and depression, but more research is needed to understand the link with other psychiatric disorders; doctors should routinely check for mental health symptoms in patients with these disorders.
Aims: To evaluate the prevalence, distress, and impact of pelvic floor dysfunction (PFD) symptomatology in women with fibromyalgia and control women. We also aimed to evaluate the impact of PFD symptomatology on several psychosocial measures such as mood, sleep, pain, and quality of life.
Methods: We conducted a cross-sectional study in women with fibromyalgia and control women from the general population.
Background And Aims: Patients with fibromyalgia frequently present with symptoms similar to those experienced by patients with gluten-related disorders, raising the possibility that a subgroup of these patients could be experiencing underlying gluten sensitivity. This study aimed to evaluate the effects of a gluten-free diet (GFD) compared with a hypocaloric diet (HCD) among patients with fibromyalgia.
Methods: Adult patients diagnosed with fibromyalgia were randomly allocated to receive a GFD or a HCD over a 24-week period.
The first two alphadelta ligands - gabapentin (GBP) and pregabalin (PGB) - were initially synthesized as antiepileptics; however, they were later also found to be useful for the treatment of additional conditions. Areas covered: Relevant publications describing potential underlying mechanisms, clinical pharmacokinetics/pharmacokinetics, and clinical efficacy and safety of these drugs in various disease conditions were searched in PubMed and Scopus and included in this review. Expert commentary: GBP and PGB are effective for the treatment neuropathic pain, fibromyalgia and epilepsy; in addition, they may be useful for the reduction of postoperative pain.
View Article and Find Full Text PDFAmitriptyline for the treatment of fibromyalgia: a comprehensive review.
Expert Rev Neurother
October 2015
Fibromyalgia is characterized by chronic generalized pain accompanied by a wide range of clinical manifestations. Most clinical practice guidelines recommend multidisciplinary treatment using a combination of pharmacological and non-pharmacological therapies. The tricyclic antidepressant amitriptyline has been most thoroughly studied in fibromyalgia.
View Article and Find Full Text PDFIntroduction: Fibromyalgia is a syndrome characterized by chronic generalized pain in addition to different symptoms such as fatigue, sleep disturbances, stiffness, cognitive impairment, and psychological distress. Multidisciplinary treatment combining pharmacological and nonpharmacological therapies is advised.
Areas Covered: Publications describing randomized controlled trials and long-term extension studies evaluating drug treatment for fibromyalgia were searched in PubMed and Scopus and included in this review.
Background: Metastases of lobular breast cancer are commonly encountered at the level of lungs, bones, brain and liver, whereas lesions in the gastrointestinal tract are rarely seen.
Case Report: A case of a patient with metastases in the right colon and gallbladder originating from an invasive lobular carcinoma is described.
Conclusion: Adequate diagnostic procedures should be performed in patients with a history of breast cancer and who show gastrointestinal symptoms to rule out the potential presence of gastrointestinal metastases.
The effects of gluten-free diet versus hypocaloric diet among patients with fibromyalgia experiencing gluten sensitivity symptoms: protocol for a pilot, open-label, randomized clinical trial.
Contemp Clin Trials
January 2015
Background: Fibromyalgia is a chronic musculoskeletal pain syndrome characterized by a broad spectrum of manifestations. Patients with fibromyalgia frequently suffer from manifestations similar to those experienced by patients with gluten-related disorders raising the possibility that some patients with fibromyalgia could suffer from underlying gluten sensitivity.
Objective: This study aims to assess whether avoiding gluten among patients with fibromyalgia and gluten sensitivity is beneficial.
Fibromyalgia is a chronic pain syndrome associated with numerous somatic symptoms including gastrointestinal manifestations of nonspecific nature. Celiac disease and nongluten sensitivity frequently evolve in adults with gastrointestinal and extraintestinal symptoms similar to those found among patients with fibromyalgia. The objective of the present study was to evaluate the presence of celiac-type symptoms among patients with fibromyalgia in comparison with healthy subjects and with those experienced by adult celiac patients and subjects with gluten sensitivity.
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