Publications by authors named "Elena N Skorodumova"
Article Synopsis
- A single exposure to ionizing radiation increases cell-free DNA (cfDNA) in blood plasma, indicating cell death, while chronic low-dose exposure reduces cfDNA levels.
- Chronic exposure leads to heightened endonuclease activity and antibody response, altering the cfDNA profile, making total cfDNA an unreliable death marker.
- Research shows that chronic exposure to radiation results in an increase in GC-rich ribosomal DNA and a decrease in AT-rich satellite DNA in cfDNA, suggesting a new marker (RrDNA/RsatIII) for monitoring chronic cellular processes related to cell death.
