Publications by authors named "Elena Morganti"
Article Synopsis
- Pluripotent cells are critical for development in eutherian embryos, transitioning from a naïve state to a primed state during gastrulation.
- The study traces the evolution of the Pou5 gene family, especially the OCT4 protein, which is key for maintaining pluripotency, highlighting its emergence in early jawed vertebrates.
- The research reveals that gene duplication led to the creation of two versions of Pou5 (Pou5f1 and Pou5f3), which have specialized roles in supporting different stages of pluripotency, thus enhancing their functions in cell self-renewal and differentiation.
Article Synopsis
- Polycaprolactone (PCL) with varying molecular weights was spin-coated on silicon wafers and treated with plasma immersion ion implantation (PIII), investigating how this treatment affects various properties of the material.
- The study found that PIII treatment leads to oxidation and hydrophobic recovery following second order kinetics, with the lowest molecular weight PCL exhibiting the highest carbonization levels.
- PIII treatment generally destroys the nano-scale lamellar structure and lowers PCL crystallinity, with cross-linking being notably higher in semi-crystalline PCL compared to amorphous forms after washing in toluene.
Matrix-assisted laser desorption ionization (MALDI) imaging mass spectrometry (MALDI-MSI) allows us to investigate the distribution of lipid molecules within tissues. We used MALDI-MSI to identify prognostic gangliosides in tissue sections of rat intracranial allografts of rat glioma and mouse intracranial xenografts of human medulloblastoma. In the healthy adult rodent brain, GM1 and GD1 were the main types of glycolipids.
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