Real-world GLP-1 RA therapy in type 2 diabetes: A long-term effectiveness observational study.

Aims: To evaluate in a real-world setting the effectiveness and tolerability of available GLP-1 RA drugs in patients with type 2 diabetes after a prolonged follow-up.

Materials And Methods: Observational, retrospective, single-centre study in patients starting GLP-1 RA therapy. Change in HbA1c, fasting plasma glucose (FPG) and body mass index (BMI) along with gastrointestinal (GI) adverse events and withdrawal from GLP-1 RA therapy were evaluated.

Photoinduced Electron Transfer in Pentaammineruthenium(II) Complexes of 1-(4-Cyanophenyl)imidazole.

A new bridging ligand, 1-(4-cyanophenyl)imidazole (CPI) has been prepared, as well as its N-methylated derivative 1-methyl-3-(4-cyanophenyl)imidazolium iodide (CPI-Me(+)I(-)). The mononuclear and binuclear complexes [(NH(3))(5)Ru-CPI-Me](3+) and [(NH(3))(5)Ru-CPI-Ru(NH(3))(5)](4+) have been obtained. Free CPI is planar, according to theoretical calculations (MMX and MNDO), and its luminescence properties suggest the occurence of a twisted internal charge transfer (TICT) state.