Publications by authors named "Elena Mejias-Lopez"
J Infect Dis
February 2024
Article Synopsis
- Congenital toxoplasmosis is a significant issue in both humans and animals, causing abortion and fetal abnormalities.
- The CDPK1 inhibitor BKI-1748 demonstrated safety in humans and effectiveness against Toxoplasma gondii in lab studies and mouse models.
- In sheep infected during pregnancy, BKI-1748 treatment began 48 hours post-infection successfully prevented abortion and congenital infection, with treated sheep showing minimal symptoms compared to untreated ones.
