Assessment of Taste and Grittiness of Riomet ER Strawberry, Riomet ER Grape, Riomet Cherry, and Metformin Immediate-Release Tablets in Healthy Subjects.

Objective: This study was conducted to evaluate the taste and grittiness of two formulations of Riomet ER (metformin hydrochloride for extended release [ER] oral suspension 100 mg/mL) differing only in their flavoring agents (strawberry and grape) in comparison with two commercially available immediate-release (IR) formulations of metformin, Riomet Cherry (metformin hydrochloride oral solution 500 mg/5 mL) and metformin IR tablets (metformin hydrochloride IR tablets 500 mg), in healthy human subjects aged 10-70 years.

Methods: Five comparison sets (i.e.