Publications by authors named "Elena Kurakina"

Sc presents a particular interest for application in nuclear medicine for positron emission tomography (PET) due to its favorable nuclear decay properties ( = 3.97 h, = 1.47 MeV, branching ratio 94.

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Radioisotope mercury-197g (Hg, half-life: 64.14 h) along with its metastable isomer (Hg, half-life: 23.8 h) are potential candidates for targeted Meitner-Auger electron therapy due to their suitable decay properties.

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Targeted Alpha Therapy (TAT) has shown very high potential for the treatment of cancers that were not responsive to other therapy options (e.g., β therapy and chemotherapy).

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Using the radiation-chemical simulation method of free radical reactions with 2,2-diphenyl-1-picrylhydrazyl, we were able to show high antiradical activity of water-ethanol extracts from . This will allow for the creation of new bioactive antioxidants based on them. The formation of silver nanoparticles (Ag-NP) was determined using the silver-ion reduction process by extracts.

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A comparative investigation of two structurally related potentially nonadentate chelating ligands, Hneunpa-NH and Hnoneunpa, has been undertaken to examine the influence of bifunctionalization on their coordination chemistry and metal ion selectivity. Significantly improved synthetic routes for each compound have been developed, employing straightforward high-yielding strategies. Radiolabeling studies with [Sc]Sc, [In]In, [Lu]Lu, and [Ac]Ac revealed a sharp contrast between the affinity of each chelator for large radiometal ions.

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Targeted Auger Therapy represents great potential for the therapy of diseases which require a high degree of selectivity on the cellular level (e.g. for therapy of metastatic cancers).

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One of the key components of radiopharmaceuticals for targeting imaging and therapy is a stable bifunctional chelating system to attach radionuclides to selective delivery systems. After-effects of radioactive decay can cause the release of a radioactive isotope from its chelation agent. Perturbed angular correlation (PAC) of γ-rays has become a unique technique to study the behavior of complexes formed between a chelating agent and radionuclide (in real time) over a relevant range of concentrations (10 M).

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Radiation chemical modeling of redox reactions of biologically active compounds from plant materials showed that coumarins possess strong antiradical properties. Data confirming the radioprotective properties of these compounds were obtained. Antioxidant activity has been shown for specific medicinal plant extracts- and cormus.

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Background: Syncope may develop in 9-35% of patients with pulmonary embolism (PE). Despite its severity and importance, the prognostic value of syncope in PE is unclear. We aimed to assess the value of syncope in patients with high-to-intermediate risk PE.

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