Angiogenesis as a Survival Mechanism in Heartworm Disease: The Role of Fructose-Bisphosphate Aldolase and Actin from in an In Vitro Endothelial Model.

Heartworm disease, caused by is a vector-borne zoonotic disease, (mainly affecting canids and felids) causing chronic vascular and pulmonary pathology in its early stages, which worsens with parasite load and/or death of adult worms in the pulmonary artery or right heart cavity, and can be fatal to the host. Angiogenesis is a mechanism by which new blood vessels are formed from existing ones. The aim of this work was to study the effect of two molecules of the excretory/secretory antigen (DiES) on the angiogenic process, taking into account that this antigen is able to interact with this process and use it as a survival mechanism.

Transmission risk of vector-borne bacterial diseases (Anaplasma spp. and Ehrlichia canis) in Spain and Portugal.

Background: Ehrlichiosis and anaplasmosis are vector-borne bacterial diseases produced by intracellular rickettsial species of the genus Ehrlichia and Anaplasma. Ehrlichia canis and Anaplasma spp. (A.

Promotes an Anti-Angiogenic Response Using an In Vitro Model of Vascular Endothelial Cells in Relation to Heartworm Disease.

Heartworm disease caused by is a vector-borne zoonotic disease responsible for the infection of mainly domestic dogs and cats, or these are those for which the most data are known. Humans are an accidental host where a benign, asymptomatic pulmonary nodule may originate. also harbours the endosymbiont bacteria of the genus , which play a role in moulting, embryogenesis, inflammatory pathology, and immune response.