Long Bone Defect Filling with Bioactive Degradable 3D-Implant: Experimental Study.

Previously, 3D-printed bone grafts made of titanium alloy with bioactive coating has shown great potential for the restoration of bone defects. Implanted into a medullary canal titanium graft with cellular structure demonstrated stimulation of the reparative osteogenesis and successful osseointegration of the graft into a single bone-implant block. The purpose of this study was to investigate osseointegration of a 3D-printed degradable polymeric implant with cellular structure as preclinical testing of a new technique for bone defect restoration.

Osteointegration technology in long bone defect reconstruction: experimental study.

Purpose: The purpose of this experimental study was to evaluate the osteointegration of a bioactive 3D-cylindrical titanium-alloy implant (bone-graft substitute) for tibial shaft defect reconstruction.

Methods: An experimental study was done in 7 mongrel dogs. Tibial shaft defect was repaired using an original titanium-alloy (Ti6Al4V) cellular cylindrical implant.

Impact of Transphyseal Elastic Nailing On the Histostructure of the Tibia in Growing Animals (Non-Randomized Controlled Experimental Study).

Background: The use of intramedullary elastic nailing is a method of choice for prevention of complications in children with osteogenesis imperfecta. However, the morphology of the growing long bones in the conditions created was not investigated.

Aim: The purpose of our experiment was to study the impact of elastic intramedullary nailing on the histostructure of long bones in their physiological growth.

Biological activity of the implant for internal fixation.

Early treatment of bone fractures was performed using implants, which are often used in the form of plates of various types, which are fixed on the bone surface (extracellular fixation) and nails that are located in the medullary canal (intracerebral fixation). The goal of this study was to investigate the features of osseointegration of implants for internal fixation (intramedullary or extramedullary) with various bioactive coating techniques. During experimental study on 20 mongrel dogs, the implant model in the form of 1.

Bioactivity and osteointegration of hydroxyapatite-coated stainless steel and titanium wires used for intramedullary osteosynthesis.

A lot of research was conducted on the use of various biomaterials in orthopedic surgery. Our study investigated the effects of nanostructured calcium-phosphate coating on metallic implants introduced into the bone marrow canal. Stainless steel or titanium 2-mm wires (groups 1 and 2, respectively), and hydroxyapatite-coated stainless steel or titanium wires of the same diameter (groups 3 and 4, respectively) were introduced into the tibial bone marrow canal of 20 dogs (each group = 5 dogs).