Radiomics for Distinguishing Myocardial Infarction from Myocarditis at Late Gadolinium Enhancement at MRI: Comparison with Subjective Visual Analysis.

Purpose: To evaluate whether radiomics features of late gadolinium enhancement (LGE) regions at cardiac MRI enable distinction between myocardial infarction (MI) and myocarditis and to compare radiomics with subjective visual analyses by readers with different experience levels.

Materials And Methods: In this retrospective, institutional review board-approved study, consecutive MRI examinations of 111 patients with MI and 62 patients with myocarditis showing LGE were included. By using open-source software, classification performances attained from two-dimensional (2D) and three-dimensional (3D) texture analysis, shape, and first-order descriptors were compared, applying five different machine learning algorithms.