Publications by authors named "Elena Gallego-Curto"
Article Synopsis
- The study investigates the effectiveness of procalcitonin (PCT) and C-reactive protein (CRP) as biomarkers for identifying bacterial coinfection in COVID-19 patients admitted to ICUs in Spain.
- Of 4,076 patients studied, only 3% had bacterial coinfection, and while PCT and CRP showed high negative predictive values, their overall predictive capability was found to be low.
- The findings indicate that measuring PCT and CRP at hospital admission is not a reliable method for diagnosing bacterial coinfection in COVID-19 pneumonia patients.
Background: The identification of critically ill COVID-19 patients at risk of fatal outcomes remains a challenge. Here, we first validated candidate microRNAs (miRNAs) as biomarkers for clinical decision-making in critically ill patients. Second, we constructed a blood miRNA classifier for the early prediction of adverse outcomes in the ICU.
View Article and Find Full Text PDFBackground: The contribution of the virus to the pathogenesis of severe COVID-19 is still unclear. We aimed to evaluate associations between viral RNA load in plasma and host response, complications, and deaths in critically ill patients with COVID-19.
Methods: We did a prospective cohort study across 23 hospitals in Spain.
Introduction: Major trauma is one of the major health care problems facing modern society, trauma systems require careful planning to achieve an ideal level of coverage for the population. The Patient Blood Management Program is an integrated and global strategy to provide patient care that aims to assess and address, when possible, the etiology of blood abnormalities rather than transfuse without treating the underlying cause. We aimed to describe the factors that are associated with the clinical decision to transfuse polytraumatized patients admitted to the Intensive Care Unit (ICU).
View Article and Find Full Text PDFArticle Synopsis
- * Conducted across 69 adult ICUs in 14 countries, the study analyzed data from 2088 patients aged 18 and older who were admitted with severe COVID-19 before April 28, 2020, excluding those with certain pre-existing conditions.
- * The findings revealed that out of 4530 admitted patients, 66.9% required invasive mechanical ventilation, highlighting the significant risk of acute brain dysfunction among severely ill COVID-19 patients.