Publications by authors named "Elena Cretu"

A raw extract and four extractive fractions were obtained from Cedrus brevifolia (Cyprus cedar) bark. They were all studied regarding the phenolic content and profile using spectrophotometry and HPLC-DAD-ESI-MS. The antioxidant activity was investigated using in vitro assays: DPPH and ABTS radicals scavenging and reducing power assays.

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Unlabelled: Cedrus brevifolia (Hook. f.) Henry, a species endemic to Cyprus, has not been studied regarding its constituents and potential biological activities.

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Unlabelled: In the Eastern Mediterranean region the wood of Pinus brutia Ten. is used as building material, the bark being the main waste of the wood production processes. A study was designed to explore possible medicinal applications for the bark waste.

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Unlabelled: The wood of mature Abies alba Mill. (silver fir) trees is used in construction and furniture industries, the bark being the main waste product.

Aim: This study aimed to investigate possible therapeutic applications of Abies alba bark waste.

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A crude hydromethanolic extract from Pinus brutia bark and its fractions (diethyl ether, ethyl acetate, n-butanol, and aqueous fractions) were studied with regard to their phenolic content and antioxidant activities. The total phenolics and proanthocyanidins in each extract were quantified by spectrophotometric methods; the polyphenolic profile was analyzed by RP-HPLC-DAD-ESI-MS. All extracts were tested with regard to their ability to scavenge free radicals (ABTS radical cation, superoxide and hydroxyl radicals), reduce ferric ions, and inhibit 15-lipoxygenase.

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Nowadays cancer is still a major public health issue. Despite all the progresses made in cancer prevention, diagnosis and treatment, mortality by cancer is on the second place after the one caused by cardiovascular diseases. The high mortality and the increasing incidence of certain cancers (lung, prostate, colorectal) justify a growing interest for the identification of new pharmacological agents efficient in cancer prevention and treatment.

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This modest study is trying to surprise the clinic shades spectrum of the pulmonary tuberculosis met at adults in the Romanati Plain zone, which was high consumption at the end of the second millennium without avoiding the new tones which AIDS and the MDR-TB brought. This things determined people to speak about the "NEW TUBERCULOSIS" of the third millennium. It had started from a number of 393 patients suffering from pulmonary tuberculosis and age over twenty.

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