Publications by authors named "Elena Collado Lledo"

Article Synopsis
  • Right ventricular failure (RVF) is a critical issue leading to high mortality rates shortly after heart transplantation, and the study explores how isoproterenol (Iso) can help improve heart function in these patients.
  • A retrospective study over one year evaluated the hemodynamic effects of Iso in 25 patients with early RVF, comparing no Iso treatment to low and high doses of Iso.
  • Results showed that Iso significantly increased heart rate and cardiac index, indicating improved heart function, while its effects on pulmonary pressures were minimal, highlighting its potential as a beneficial treatment for RVF post-heart transplant.
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Article Synopsis
  • The study examines the recurrence of ventilator-associated pneumonia (VAP) in patients with severe COVID-19 treated with ECMO, highlighting how common VAP recurrence is among this group.
  • Out of 210 patients who developed initial VAP, 82% experienced a recurrence, typically within 10 days, predominantly caused by Enterobacteriaceae and Pseudomonas aeruginosa.
  • The duration of antibiotic treatment for the first episode (short course <8 days vs. prolonged course ≥8 days) did not significantly impact the likelihood of VAP recurrence.
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Article Synopsis
  • There are recognized differences between men and women in demographics and clinical characteristics of heart failure, which affect management and outcomes, particularly in acute heart failure and cardiogenic shock.
  • Recent studies show women with acute heart failure are generally older, more likely to have preserved ejection fraction, and less frequently have ischemic causes, but they often receive less aggressive treatment than men, despite similar outcomes being reported.
  • More research including female patients is needed to better understand these sex-related differences and improve overall treatment equality in heart failure management.
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Article Synopsis
  • Early recognition and risk stratification are important for managing cardiogenic shock (CS), but there are concerns about lower adherence to recommendations in women with cardiovascular diseases.
  • Data from the Red-Shock registry included 793 patients, revealing that women were older and had different health backgrounds but showed similar treatment approaches and in-hospital mortality rates compared to men.
  • Both CardShock and IABP-SHOCK II risk scores were effective in predicting in-hospital mortality for both men and women, indicating that gender does not significantly affect management or outcomes in CS.
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Background: Mortality from cardiogenic shock remains high and early recognition and risk stratification are mandatory for optimal patient allocation and to guide treatment strategy. The CardShock and the Intra-Aortic Balloon Counterpulsation in Acute Myocardial Infarction Complicated by Cardiogenic Shock (IABP-SHOCK II) risk scores have shown good results in predicting short-term mortality in cardiogenic shock. However, to date, they have not been compared in a large cohort of ischaemic and non-ischaemic real-world cardiogenic shock patients.

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