Publications by authors named "Elena Casali"

Article Synopsis
  • * A specific challenging case of S. maltophilia BSI due to septic thrombosis is presented, where the infection was successfully treated using cefiderocol in addition to levofloxacin.
  • * The treatment plan also included an intra-lock therapy with trimethoprim/sulfamethoxazole to prevent reinfection, as full resolution of the infection source was not achievable, supported by a serum bactericidal assay to confirm the treatment's effectiveness.
View Article and Find Full Text PDF

Background: Remdesivir (REM) has shown potent antiviral activity and efficacy in animal models of COVID-19; nevertheless, clinical trials and real-life reports have shown conflicting data on its effectiveness. Aims of the study were to evaluate the impact of remdesivir on I) Intensive Care Unit (ICU) admission, II) need for orotracheal intubation (OTI) and III) in-hospital mortality. Furthermore, we estimated the kinetics of laboratory parameters and assessed the risk factors for in-hospital mortality in the remdesivir population.

View Article and Find Full Text PDF

The emergency caused by Covid-19 pandemic raised interest in studying lifestyles and comorbidities as important determinants of poor Covid-19 prognosis. Data on tobacco smoking, alcohol consumption and obesity are still limited, while no data are available on the role of e-cigarettes and heated tobacco products (HTP). To clarify the role of tobacco smoking and other lifestyle habits on COVID-19 severity and progression, we designed a longitudinal observational study titled COvid19 and SMOking in ITaly (COSMO-IT).

View Article and Find Full Text PDF