High-Pressure Bulk Synthesis of InN by Solid-State Reaction of Binary Oxide in a Multi-Anvil Apparatus.

We present a new method to synthesize bulk indium nitride by means of a simple solid-state chemical reaction carried out under hydrostatic high-pressure/high-temperature conditions in a multi-anvil apparatus, not involving gases or solvents during the process. The reaction occurs between the binary oxide InO and the highly reactive LiN as the nitrogen source, in the powder form. The formation of the hexagonal phase of InN, occurring at 350 °C and ≥ 3 GPa, was successfully confirmed by powder X-ray diffraction, with the presence of LiO as a unique byproduct.

Potential effectiveness of Ospemifene on Detrusor Overactivity in patients with vaginal atrophy.

Objectives: To report the effects on the urinary function of ospemifene prescribed for vulvovaginal atrophy (VVA) in patients with overactive bladder (OAB) symptoms refractory to the first line of pharmacologic treatment with antimuscarinic or β3-agonists drugs. We also try to identify any predictors of response to the ospemifene treatment.

Study Design: Twenty-five patients with OAB confirmed by detrusor overactivity at urodynamics, refractory to first-line therapy for OAB, were enrolled for the study.