Publications by authors named "Elena Betore"
Sex-related differences in the presentation, management and response to treatment of eosinophilic esophagitis: Cross sectional analysis of EoE CONNECT registry.
United European Gastroenterol J
December 2024
Background: Eosinophilic esophagitis (EoE) predominantly affects males across all ages; however, little is known about sex differences for other aspects of EoE.
Objective: To investigate associations between sex and clinical presentation, endoscopic features, treatment choice and response in EoE patients in real-world practice.
Methods: Cross-sectional analysis of the multicenter EoE CONNECT registry.
This study compared short-term effectiveness of proton pump inhibitors (PPI), swallowed topical corticosteroids (STC), and dietary therapies in reversing clinical and histological features in pediatric patients with eosinophilic esophagitits (EoE). Determinants for treatment choice and PPI therapy effectiveness were also assessed. A cross-sectional study analysis of patients under 18 years old recruited onto the multicenter EoE CONNECT registry was performed.
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- Swallowed topical corticosteroids (tC) are commonly used to treat eosinophilic esophagitis (EoE), but their effectiveness varies due to different formulations and doses.
- A study analyzed data from the EoE CONNECT registry, focusing on clinical and histological remission rates based on various tC treatments used in real-world settings.
- Results showed that higher doses (≥0.8 mg/day) improved remission rates, budesonide orodispersible tablets were the most effective, and factors like reduced symptom severity influenced treatment outcomes.
Article Synopsis
- * A study of 520 adult patients showed that small abscesses (<30 mm) can be treated effectively with antibiotics, while larger abscesses require drainage methods, with surgical drainage being more effective but riskier.
- * Post-treatment, luminal resection lowers the risk of abscess recurrence within a year, but anti-TNF therapy shows similar effectiveness for preventing recurrences regardless of resection.
Background: Poor adherence to clinical practice guidelines for eosinophilic esophagitis (EoE) has been described and the diagnostic delay of the disease continues to be unacceptable in many settings.
Objective: To analyze the impact of improved knowledge provided by the successive international clinical practice guidelines on reducing diagnostic delay and improving the diagnostic process for European patients with EoE.
Methods: Cross-sectional analysis of the EoE CONNECT registry based on clinical practice.