Publications by authors named "Elena Aleshkovich"
MicroRNAs as Novel Biomarkers for P2Y12 - Inhibitors Resistance Prediction.
Pharmgenomics Pers Med
December 2021
Article Synopsis
- The study aims to evaluate six micro-RNAs as potential biomarkers for predicting resistance to P2Y12-inhibitors in patients with acute coronary syndrome.
- Eighty patients treated with either ticagrelor or clopidogrel underwent genotyping to assess specific polymorphisms and measured expression levels of the six miRNAs, with results correlating to platelet reactivity.
- The findings suggest that miR-29, miR-34, miR-126, miR-142, and miR-223 could serve as valuable biomarkers for identifying P2Y12-inhibitor resistance, potentially replacing traditional platelet reactivity tests.