Publications by authors named "Elena A Malingriaux"
Article Synopsis
- The production of reactive oxygen species (ROS) in mitochondria is influenced by proton motive force and can be reduced by mild uncoupling through mitochondrial uncoupling proteins (UCPs), which may also be activated by ROS.
- Research on the effects of 4-hydroxy-2-nonenal (HNE) on mitochondria shows that HNE does not directly activate UCP1 or UCP2, but enhances membrane conductance when combined with long-chain fatty acids.
- The increase in conductance is concentration-dependent and suggests that both lipid and protein mechanisms are involved, with a focus on the role of fatty acids and potential interactions between HNE and specific amino acids in UCPs.
