Publications by authors named "Elen de Lacy"
Third doses of COVID-19 vaccines were widely deployed following the primary vaccine course waning and the emergence of the Omicron-variant. We investigated protection from third-dose vaccines and previous infection against SARS-CoV-2 infection during Delta-variant and Omicron-variant (BA.1 & BA.
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- The SIREN study began in June 2020, focusing on PCR testing and sequencing in UK healthcare workers to monitor SARS-CoV-2 infections and reinfections.
- It identified a rise in infections and reinfections, as well as the emergence of Omicron subvariant waves, aligning with national data.
- SIREN's approach serves as an effective method for ongoing variant surveillance.
Article Synopsis
- - The study examined how long immunity lasts from both infection and vaccination against SARS-CoV-2 among asymptomatic healthcare workers in the UK, aiming to inform guidelines for booster shots.
- - Researchers tracked 35,768 healthcare workers and found that 95% were vaccinated; a significant decline in vaccine effectiveness was observed over time, particularly among those who received the BNT162b2 vaccine (Pfizer-BioNTech).
- - Vaccine effectiveness dropped from 85% shortly after vaccination to 51% after about 200 days, with little difference noted between those who received long or short intervals between doses of the same vaccine.
Objectives: To examine the prevalence and frequency of electronic (e)-cigarette use among young people in Wales, associations with socio-demographic characteristics, smoking and other substances and the sequencing of e-cigarette and tobacco use.
Design: A cross-sectional survey of school students in Wales undertaken in 2015.
Setting: 87 secondary schools in Wales.