Publications by authors named "Eleftherios Pavlou"
Article Synopsis
- An emerging multidrug-resistant fungal pathogen presents challenges in healthcare due to high misidentification and treatment resistance, highlighting a need for better identification methods.
- The study utilized Raman spectroscopy on fungal cultures grown on modified Dixon's agar to differentiate among species, identifying key spectral markers that distinguish them into subgroups and using principal component analysis (PCA) for further differentiation.
- The research also revealed a unique spectral signature for the modified agar, showcasing Raman spectroscopy's ability for real-time, non-destructive identification, despite the challenges posed by spectral similarity and variability among closely related fungi.
Article Synopsis
- Monitoring skin cancer treatment is difficult, and confirming tumor presence after treatment is crucial for spotting relapses early.
- Optical coherence tomography (OCT) offers a non-invasive way to image skin lesions like basal cell carcinomas but struggles with image quality due to light scattering and observer subjectivity.
- This study presents a new method using advanced image processing techniques to improve OCT image resolution and accurately differentiate between tumor tissue and scar tissue after cryosurgery.
BCC (basal cell carcinoma) and SCC (squamous cell carcinoma) account for the vast majority of cases of non-melanoma skin cancer (NMSC). The gold standard for the diagnosis remains biopsy, which, however, is an invasive and time-consuming procedure. In this study, we employed spatially offset Raman spectroscopy (SORS), a non-invasive approach, allowing the assessment of deeper skin tissue levels and collection of Raman photons with a bias towards the different layers of epidermis, where the non-melanoma cancers are initially formed and expand.
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- Greece has many PDO cheese products with significant export activity, and this study aimed to analyze the microbial communities of six well-known cheeses using advanced sequencing technology.
- The analysis revealed varying levels of bacterial species richness and diversity among the cheeses, with lactic acid bacteria being predominant in all samples, while specific fungal populations also contributed to the unique flavors.
- The findings suggest that while certain microbes are common, their specific contributions to each cheese type are influenced by production methods and ingredients, paving the way for developing a core microbial signature that can enhance the reputation of Greek cheeses.
Malassezia yeasts constitute the major eukaryotic cutaneous flora of homoeothermic vertebrates. These lipophilic yeasts are able to cause, trigger, or aggravate common skin diseases under favorable conditions. Species identification and subspecies differentiation is currently based on morphological characteristics, lipid assimilation profile, and molecular tests.
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