Publications by authors named "Eleazar Israel Perez-Lopez"
Article Synopsis
- B-cell acute lymphoblastic leukemia is the most common cancer in children, especially in Mexico, with over 30% of patients facing relapse and poor outcomes despite a high five-year survival rate.
- Research into gene expression profiles has identified certain transcripts that can help predict disease prognosis, particularly focusing on the ZNF695 gene, which has multiple transcript variants due to alternative splicing.
- In studies, the ZNF695 variants were found to be predominantly expressed in leukemia patients' bone marrow, and notably, the expression levels of long noncoding RNA ZNF695 were linked to survival rates.
Droplet digital PCR is the most robust method for absolute nucleic acid quantification. However, RNA is a very versatile molecule and its abundance is tissue-dependent. RNA quantification is dependent on a reference control to estimate the abundance.
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