Publications by authors named "Eleanor Toomey"
Article Synopsis
- - ANT3310 is a new drug being tested alongside meropenem (MEM) to treat serious infections caused by drug-resistant bacteria, specifically carbapenem-resistant Gram-negative pathogens.
- - In tests with 905 clinical bacterial isolates, the combination of MEM and ANT3310 showed significantly better antibacterial activity, reducing MIC values for carbapenem-resistant Enterobacterales from over 32 µg/mL to much lower levels.
- - The combination of MEM and ANT3310 effectively inhibited the growth of nearly all tested resistant strains and proved effective in mouse models of thigh and lung infections, showing promise as a treatment option compared to other existing drug combinations.