Publications by authors named "Eleanor Ford"
Article Synopsis
- The study focuses on patients with primary rectal adenocarcinoma who underwent neoadjuvant chemoradiotherapy and achieved a pathological complete response (pCR), aiming to determine long-term outcomes and predictors of pCR.
- A review of medical records from 2000 to 2012 revealed that out of 380 patients, 277 received the treatment, and 46 achieved pCR, which was associated with significantly better overall and disease-free survival.
- Key factors associated with achieving a pCR included tumor height above the anal verge, low lymph node yield, high pre-operative hemoglobin levels, and low neutrophil-lymphocyte ratios, with tumor height being notably significant in multivariable analysis.
Objective: To create a multi-site registry to enable future large-scale studies of perinatal depression among women attending obstetrics clinics in the USA.
Methods: A screening and recruitment registry was developed that included women aged at least 18 years who attended seven obstetric clinics in the University of Michigan Health System (Ann Arbor, MI, USA) for prenatal care between September 8, 2008, and June 9, 2011. Participants completed depression screening and research recruitment materials.
Nek2 is a cell cycle-regulated serine/threonine protein kinase that is up-regulated in human cancers. Functionally, it is implicated in control of centrosome separation and bipolar spindle formation in mitotic cells and chromatin condensation in meiotic cells. Two major splice variants have been described in vertebrates, Nek2A and Nek2B, that differ in their non-catalytic C termini.
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