Public Health.

Background: Early life-course exposome, including area-based social disadvantage, may influence the development of cognitive reserve, thereby impacting later-life incidence of Alzheimer's Disease and Related Dementias (ADRD). The primary goal of this scoping review is to evaluate the extent of literature examining early-life exposure to area-based disadvantage and its association with structural neuroanatomical differences. A secondary goal is to examine the commonalities in brain regions impacted as well as the components of the exposure-metrics utilized to study the social exposome.

Deriving life-course residential histories in brain bank cohorts: A feasibility study.

Introduction: The exposome is theorized to interact with biological mechanisms to influence risk for Alzheimer's disease but is not well-integrated into existing Alzheimer's Disease Research Center (ADRC) brain bank data collection.

Methods: We apply public data tracing, an iterative, dual abstraction and validation process rooted in rigorous historic archival methods, to develop life-course residential histories for 1254 ADRC decedents.

Results: The median percentage of the life course with an address is 78.

A systematic review of the engagement with social media-delivered interventions for improving health outcomes among sexual and gender minorities.

Background: Sexual and gender minority (SGM) persons face a number of physical and mental health disparities closely linked to discrimination, social stigma, and victimization. Despite the acceptability and increasing number of digital health interventions focused on improving health outcomes among SGM people, there is a lack of reviews summarizing whether and how researchers assess engagement with social media-delivered health interventions for this group.

Objective: The objective of this systematic review was to synthesize and critique the evidence on evaluation of engagement with social media-delivered interventions for improving health outcomes among SGM persons.

"I Don't Feel Like the Odd One": Utilizing Content Analysis to Compare the Effects of Social Media Use on Well-Being Among Sexual Minority and Nonminority US Young Adults.

Purpose: Although there is evidence of associations between social media (SM) use and mental well-being among the general population, these associations among lesbian, gay, and bisexual (LGB) persons are poorly understood. This study compared the influence of SM experiences on mental well-being between LGB and non-LGB persons.

Design And Setting: Online cross-sectional survey.