Quality-by-design driven approach in the formulation of an anti-ulcer and gastro-protective oral suspension.

Objective: This work aims to present a Quality-by-Design (QbD) step-by-step methodology to formulate anti-ulcer and gastro-protective oral suspensions.

Methods: Sucralfate was used as a drug model. The Quality Target Product Profile was established early during preformulation.

Development of immediate release Rupatadine fumarate 10 mg tablets: A Quality by Design (QbD) approach.

The main objective of this research is to develop an immediate release Rupatadine fumarate 10 mg tablets formulation by direct compression, through a Quality by Design approach in Costa Rica. According to a Quality by Design approach; Target Product Profile, Quality Target Product Profile, and the Critical Quality Attributes were defined. In the preformulation study, compatibility tests were carried out between the raw materials.