The Effect of Age on High-Dose Therapy with Autologous Stem Cell Support in Multiple Myeloma: A Single-Center Experience.

This retrospective one-center study demonstrates the complications related to high-dose therapy with autologous stem cell support (HDT) and the survival of multiple myeloma (MM) patients according to age groups. : We categorized the patients into two groups: those who were ≤65 years old (group 1) ( = 115) and those who were >65 years old (group 2) ( = 26). The mean duration of follow-up was 48 (1-125) months.

Coexistence of Takayasu arteritis and chronic myeloid leukemia: Coincidental or paraneoplastic phenomenon?

Vasculitis may rarely be seen in the course of myeloproliferative neoplasms (MPN). In vasculitis associated with hematological diseases, mostly small- and medium-vessel involvement is expected, aortitis is very rare. It is not exactly known whether large-vessel vasculitis associated with MPN is a paraneoplastic phenomenon or coincidental.

Does insulin resistance trigger thyroid nodule?

The relationship between insulin resistance and thyroid nodules is not clearly understood. The purpose of this study is to investigate the relationship between insülin resistance and thyroid nodules in non-diabetic patients. 410 patients who applied to the Internal Medicine outpatient clinic from June 2018 to July 2019 were reviewed retrospectively.

Relationship Between the Neutrophil to Lymphocyte Ratio and the Presence and Size of Thyroid Nodules.

Aim To investigate the possible relationship between the neutrophil to lymphocyte ratio (NLR) value and the presence and size of thyroid nodules. Patients and methods Data of 216 patients between 18 and 65 years of age, who had presented to the internal medicine department of our hospital between February 2018 and September 2018, were collected retrospectively. A total of 216 patients fulfilling the inclusion criteria were included in the study.

Protective Effect of All-Trans Retinoic Acid in Cisplatin-Induced Testicular Damage in Rats.

Purpose: To investigate the effects of all-trans retinoic acid (ATRA) in cisplatin (CP)-induced testicular damage in rats.

Materials And Methods: Twenty-eight male Wistar rats were divided into four groups: Control, ATRA alone, ATRA+CP, and CP alone. Body weight, testicular weight, sperm count, sperm motility, percentage of abnormal sperm, total antioxidant status (TAS), total oxidant status (TOS), oxidative stress index (OSI) in testicular tissue, and testicular histopathology were compared among groups.

All-trans retinoic acid prevents cisplatin-induced nephrotoxicity in rats.

The aim of this study is to investigate the effects of all-trans retinoic acid (ATRA) use on cisplatin (CP)-induced nephrotoxicty. Twenty-eight rats were randomly divided into four groups. The rats in the control group were injected a single dose of 1 ml/kg saline intra-peritoneally (IP) during 10 days.