The Influence of Topical Cyclopentolate Instillation on Peripapillary and Macular Microvasculature Measured by Optical Coherence Tomography Angiography in Healthy Individuals.

Purpose: To investigate the influence of topical cyclopentolate 1%, as an anti-muscarinic mydriatic agent, on the peripapillary and macular microvasculature by optical coherence tomography angiography (OCT-A) in healthy adults.

Methods: A total of 41 healthy adults without any systemic or ocular disease were enrolled for this prospective consecutive study. All patients underwent OCT-A measurements (OptoVue Inc.

The diagnostic value of systemic immune-inflammation index in diabetic macular oedema.

Clinical Relevance: Diabetic macular oedema (DME) is a significant cause of visual impairment and inflammation plays an important role in its pathophysiology.

Background: This study evaluates the diagnostic value of systemic immune-inflammation index (SII) in the occurrence of DME in patients with non-proliferative diabetic retinopathy.

Methods: In this prospective study, the SII was applied to 150 consecutive patients with non-proliferative diabetic retinopathy.

Investigation of the Retinal and Optic Disc Microvascularization in Polycystic Ovary Syndrome: An Optical Coherence Tomography Angiography Study.

Purpose: To investigate retinal and optic disc microvascular alterations using optical coherence tomography angiography (OCTA) in women with polycystic ovary syndrome (PCOS).

Methods: Forty-six eyes of 23 patients with PCOS (PCOS group), and 50 eyes of 25 sex and age-matched healthy controls (control group) were included in this cross-sectional study. Foveal retinal thickness, peripapillary retinal nerve fiber layer (RNFL) thickness, vessel density in different sections of the retina and optic disc were analyzed by OCTA.

Assessment of Red Cell Distribution Width, Platelet/lymphocyte Ratio, Systemic Immune-inflammation Index, and Neutrophil/lymphocyte Ratio Values in Patients with Central Retinal Artery Occlusion.

Purpose: To evaluate complete blood count (CBC)-derived inflammatory indices in central retinal artery occlusion (CRAO).

Methods: A total of 42 patients with CRAO (CRAO group) and 42 age- and sex-matched subjects without CRAO (Control group) were included. CBC parameters including red cell distribution width (RDW) levels were assayed.

Evaluation of systemic immune-inflammation index level as a novel marker for severity of noninfectious uveitis.

Purpose: To evaluate the association of systemic immune-inflammation index (SII) levels, neutrophil/lymphocyte ratio (NLR), and platelet/lymphocyte ratio (PLR) with severity of noninfectious uveitis.

Methods: This retrospective study included 46 patients with noninfectious uveitis (uveitis group) and 46 age- and sex-matched healthy subjects (control group). The demographic and ocular findings, localization, and activity of uveitis were recorded at the time of onset evaluation.

Corneal endothelial cell density and microvascular changes of retina and optic disc in autosomal dominant polycystic kidney disease.

Purpose: Vascular endothelial dysfunction in autosomal dominant polycystic kidney disease (ADPKD) may affect the retinal vascular parameters due to structural similarities of kidney and retina. We aimed to evaluate the microvascular changes of retina and optic disc and also corneal endothelial cell density in patients with ADPKD.

Methods: Forty-six eyes of 23 patients with ADPKD (Group 1), and 46 eyes of 23 sex- and age-matched healthy controls (Group 2) were included in this cross-sectional study.

Systemic immune-inflammation index, neutrophil-to-lymphocyte ratio, and platelet-to-lymphocyte ratio levels are associated with keratoconus.

Purpose: The aim of this study was to assess the systemic immune-inflammation index (SII) levels, neutrophil-to-lymphocyte ratio (NLR), and platelet-to-lymphocyte ratio (PLR) in patients with keratoconus (KC).

Methods: A total of 42 patients with KC (KC group) and 42 age- and sex-matched healthy subjects (control group) were included into this cross sectional study. Complete blood count parameters were assayed.

Association of childhood obesity with retinal microvasculature and corneal endothelial cell morphology.

Objectives: To investigate the optical coherence tomography angiography (OCTA) and specular microscopy (SM) findings in obese children and compare them with healthy ones.

Methods: In this prospective study, 50 eyes of 25 obese children [body mass index (BMI) ≥95th percentile], 36 eyes of 18 control age- and sex- matched healthy subjects (BMI <85th percentile) were included. Demographic features and ophthalmological examination including OCTA measurements as well as SM findings were assessed.

Plasminogen activator inhibitor-1 4G/5G polymorphism and dyslipidemia with branch retinal artery occlusion in a young lady.

Branch retinal artery occlusion (BRAO) leads obstruction of blood flow in the distribution of the affected vessel giving rise to ischemia and reorganization of the retinal layers. It is a very rare diagnosis and the etiological risk factors of BRAO are not clean in the young population. Various hypercoagulable states leading to thrombosis appeared to be more responsible.

A Series of Civilian Ocular Injuries from the Civil War in Syria.

Objectives: This study aimed to evaluate the demographic and clinical features of eye injury cases in the Syrian Civil War.

Methods: A total of 224 eyes of 212 Syrian patients who were referred urgently to Hatay Mustafa Kemal University Faculty of Medicine Department of Ophthalmology between January 2011 and December 2018 were evaluated retrospectively. Types of trauma and clinical findings were analyzed.

Assessment of platelet-to-lymphocyte ratio in patients with retinal vein occlusion.

Purpose: To investigate platelet-to-lymphocyte ratio (PLR) in retinal vein occlusion (RVO) patients.

Methods: In this study, we retrospectively reviewed data of 32 patients with RVO (RVO group) and 32 age- and sex-matched participants without RVO (control group) between January 2017 and March 2019. The PLR was determined by dividing the platelet count by the lymphocyte count.

Increased Systemic Immune-Inflammation Index Levels in Patients with Dry Eye Disease.

Purpose: To evaluate the systemic immune-inflammation index (SII) levels, neutrophil-to-lymphocyte ratio (NLR), and platelet-to-lymphocyte ratio (PLR) in patients with dry eye disease (DED) and to compare with control subjects.

Methods: This prospective study included 47 DED patients and 47 age- and sex-matched healthy controls. Ophthalmological examination, diagnostic DED tests, and routine complete blood cell count parameters were analyzed.

Schnyder Corneal Dystrophy: A Rare Case Report.

Introduction: Schnyder corneal dystrophy (SCD) is a rare, autosomal dominant, anterior stromal dystrophy described as progressive bilateral corneal opacification due to abnormal accumulation of cholesterol and phospholipids in the cornea. The clinical signs can change as the patient ages. SCD with different presentations may actually be misdiagnosed.

Valsalva Maculopathy Associated with a Sudden, Forceful Shout.

Valsalva maculopathy (VM) induced by the Valsalva maneuver may cause a sudden, painless, and dramatic loss of vision in healthy individuals due to a premacular location of the hemorrhage and rupture of retinal capillaries. The prognosis is generally good. The hemorrhage usually clears spontaneously without any treatment.

Comparison of sugammadex and neostigmine-atropine on intraocular pressure and postoperative effects.

During surgery, changes in intraocular pressure (IOP) can be observed resulting from several factors, such as airway manipulations and drugs used. We aimed to investigate the effects of sugammadex and neostigmine on IOP, hemodynamic parameters, and complications after extubation. Our study comprised 60 patients, aged 18-65 years, with a risk status of the American Society of Anesthesiologists I-II who underwent arthroscopic surgery under general anesthesia.

Changes in retinal vessels related to varicocele: a pilot investigation.

The aim of this study was to investigate whether retinal vasculature changes had occurred (retinal artery diameter, retinal vein diameter and artery/vein ratio) in patients with varicocele. This pilot study included 50 healthy subjects with any eye disease apart from slight refractive errors and 55 patients with varicocele. Retinal arteriolar and venular diameters were measured and summarised as central retinal arteriolar equivalent (CRAE) and central retinal venular equivalent (CRVE).

Changes in the cornea related to sickle cell disease: a pilot investigation.

Purpose: To investigate corneal structural changes (central corneal thickness, endothelial cell count, and cellular morphology) in patients with sickle cell disease (SCD).

Methods: This prospective study included 56 patients with SCD and 50 age- and sex-matched healthy subjects without any eye disease aside from refractive errors. Endothelial cell density (ECD), percentage of hexagonality, and the coefficient of variation in cell size (CV) were measured using noncontact specular microscopy, and central corneal thickness (CCT) was measured by pachymetry.

Effect of intravitreal injection of dexamethasone implant on corneal endothelium in macular edema due to retinal vein occlusion.

Objective: To evaluate the effects of dexamethasone (DEX) implant (Ozurdex(®)) on corneal endothelium in patients with retinal vein occlusion complicated with macular edema.

Materials And Methods: Patients (n = 31) received 1-3 intravitreal DEX implants in one eye. Measurements were intraocular pressure (IOP) at baseline and 1, 3, and 6 months after the first intravitreal injection and corneal specular microscopy and central corneal thickness (CCT) at baseline and 1 and 6 months.

Scheimpflug imaging in dermatochalasis patients before and after upper eyelid blepharoplasty.

Purpose: The aim of this study was to evaluate corneal parameters obtained by Scheimpflug imaging of dermatochalasis patients both preoperatively and after blepharoplasty.

Materials And Methods: Sixty eyes of 30 patients (22 female, 8 male), which were operated upon for the upper eyelid, were included in the study. Patients were divided into two groups according to preoperative upper margin reflex distance (MRD): MRD < 2.

Myositic type of idiopathic orbital pseudotumor in a 4-year-old child: a case report.

Idiopathic orbital pseudotumor is a benign, noninfectious, and nonneoplastic disease with unknown cause. It is the third most common orbital disease after thyroid orbitopathy and lymphoproliferative disorder. Idiopathic orbital pseudotumor is extremely rare in pediatric age group and may cause real diagnostic problems.