Publications by authors named "Elbadawi A"
Background: The comparative outcomes with immediate, staged in-hospital, and staged out-of-hospital complete revascularization for patients with ST-segment-elevation myocardial infarction and multivessel disease remain unclear.
Methods And Results: An electronic search of MEDLINE, SCOPUS, and Cochrane databases was performed through August 2023 for randomized trials evaluating immediate, staged in-hospital, and staged out-of-hospital complete revascularization for patients with ST-segment-elevation myocardial infarction and multivessel disease. The primary outcome was major adverse cardiac events (MACEs).
Article Synopsis
- A systematic review of five clinical trials involving over 21,000 patients analyzed the effectiveness of abbreviated ticagrelor-based dual antiplatelet therapy (DAPT) compared to the standard 12-month therapy in patients with acute coronary syndrome (ACS).
- Results indicated that abbreviated DAPT (≤3 months) significantly reduced all-cause mortality risk (risk ratio 0.78) without differences in major cardiac events like myocardial infarction or stent thrombosis.
- Additionally, the abbreviated DAPT was linked to a lower risk of major bleeding complications, suggesting potential benefits in reducing adverse outcomes while maintaining similar effectiveness for key cardiac events.
Article Synopsis
- The study investigates the link between hospital volumes for aortic valve replacement (AVR) surgeries—either transcatheter (TAVR) or surgical (SAVR)—and patient outcomes, specifically in-hospital mortality and 30-day readmission rates.
- It classified hospitals based on their procedural volumes and analyzed data from over 72,000 patients across 400 U.S. hospitals, finding that higher hospital volumes are associated with lower in-hospital mortality but do not affect 30-day readmissions.
- The conclusions suggest that patients with aortic stenosis have better outcomes when treated in high-volume hospitals that perform both TAVR and SAVR procedures frequently.
Background: Pulmonary embolism is one of the leading causes of morbidity and mortality in the United States. Catheter-directed therapies have emerged as a promising treatment for managing intermediate- and high-risk patients; however, data comparing standard catheter-directed thrombolysis (SCDT) and ultrasound-assisted thrombolysis (USAT) are limited. This study aimed to investigate trends, outcomes, and predictors of mortality of both modalities from a nationally representative sample.
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- This study examined the link between participating in clinical trials and the rates of unplanned readmissions within 30 days for patients with acute coronary syndrome (ACS).
- Analysis of data covering over 2 million ACS cases showed no significant difference in readmission rates between trial participants and non-participants.
- Non-participants had higher rates of readmissions due to cardiovascular issues, while trial participants experienced more complications, such as bleeding and strokes, during readmission.
Background: Data on outcomes of patients with high-risk acute pulmonary embolism (PE) transferred from other hospitals are scarce.
Methods: We queried the Nationwide Readmissions Database for admissions who were ≥18 years old, and with a primary discharge diagnosis of acute high-risk PE between the years 2016 and 2019. The main outcome of interest was the difference in all-cause in-hospital mortality between patients admitted directly to small/medium hospitals; patients admitted directly to large hospitals; and patients transferred to large hospitals.
Background: Randomized controlled trials (RCTs) examining the outcomes with limus drug-coated balloons (DCBs) vs paclitaxel DCBs were small and underpowered for clinical endpoints.
Objectives: This study sought to compare the angiographic and clinical outcomes with limus DCBs vs paclitaxel DCBs for percutaneous coronary intervention (PCI).
Methods: An electronic search of Medline, EMBASE, and Cochrane databases was performed through January 2024 for RCTs comparing limus DCBs vs paclitaxel DCBs for PCI.
Article Synopsis
- The study aimed to compare the outcomes of intravascular ultrasound (IVUS) and conventional coronary angiography in patients undergoing complex percutaneous coronary intervention (PCI).
- A meta-analysis of 10 randomized clinical trials involving 6,615 patients showed that IVUS significantly reduced major adverse clinical events (MACE) like cardiac death and stent thrombosis compared to coronary angiography.
- The results indicated no significant difference between the two groups regarding all-cause death and myocardial infarction, highlighting IVUS's potential benefits in improving PCI outcomes.
Background: Patients with lymphedema and lipedema share physical exam findings that may lead to misdiagnosis. Poor mobility is common in patients with obesity and patients with lymphedema and lipedema. This may constitute a risk factor for venous thromboembolism (VTE).
View Article and Find Full Text PDFImportance: Preclinical studies suggest a potential role for aspirin in slowing abdominal aortic aneurysm (AAA) progression and preventing rupture. Evidence on the clinical benefit of aspirin in AAA from human studies is lacking.
Objective: To investigate the association of aspirin use with aneurysm progression and long-term clinical outcomes in patients with AAA.
Patients with hematologic malignancies (HMs) are at risk of future cardiovascular (CV) events. We therefore conducted a systematic review and meta-analysis to quantify their risk of future CV events. We searched Medline and EMBASE databases from inception until January 31, 2023 for relevant articles using a combination of keywords and medical subject headings.
View Article and Find Full Text PDFBackground: This study aimed to determine the prevalence and associated characteristics of needle stick and sharp injuries (NSSIs) among King Salman Armed Forces Hospital (KSAFH) personnel.
Methods: Data was collected by reviewing all reported NSSIs among KSAFH personnel between January 2020 to December 2022.
Results: The prevalence of NSSIs was 2.
Purpose: Focal chondral lesions of the femur are currently treated with biological repair or arthroplasty. However, some patients are not suitable for either one due to lesion size, age, or prior biological treatment attempts. While singular patient-specific focal mini metal implants already showed good results, the outcomes of bicompartmental implantation of these implants have not been discussed in the literature yet.
View Article and Find Full Text PDFCoronary angiography has a limited ability to predict the functional significance of intermediate coronary lesions. Hence, physiological assessment of coronary lesions, via fractional flow reserve (FFR) or instantaneous wave-free ratio (iFR), has been introduced to determine their functional significance. An accumulating body of evidence has consolidated the role of physiology-guided revascularization, particularly among patients with stable ischemic heart disease.
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