Publications by authors named "Elangwe M Sarah-Matio"
Background: Sickle cell trait (SCT) refers to the carriage of one abnormal copy of the β-globin gene, the HbS allele. SCT offers protection against malaria, controlling parasite density and preventing progression to symptomatic malaria. However, it remains unclear whether SCT also affects transmission stages and mosquito infection parameters.
View Article and Find Full Text PDFMalaria control relies on passive case detection, and this strategy fails detecting asymptomatic infections. In addition, infections in endemic areas harbor multiple parasite genotypes that could affect case management and malaria epidemiology. Here, we performed AmpSeq genotyping to capture polymorphisms associated with antimalarial resistance and the genetic diversity within natural Plasmodium falciparum infections.
View Article and Find Full Text PDFCorrection to: Epidemiological and entomological studies of malaria transmission in Tibati, Adamawa region of Cameroon 6 years following the introduction of long-lasting insecticide nets.
Parasit Vectors
October 2021
Antimalarial drug resistance in the Central and Adamawa regions of Cameroon: Prevalence of mutations in P. falciparum crt, Pfmdr1, Pfdhfr and Pfdhps genes.
PLoS One
July 2024
Article Synopsis
- The study focuses on the prevalence of drug-resistant malaria parasites (Plasmodium falciparum) in Cameroon, emphasizing the importance of monitoring genetic mutations related to antimalarial resistance.
- Results indicated a high occurrence of specific mutations in drug resistance genes, with significant differences reported between two distinct regions (Mfou and Tibati).
- Notably, a quadruple resistant genotype was found in almost 90% of samples, highlighting a concerning trend in resistance patterns that may impact malaria control efforts in Sub Saharan Africa.
Epidemiological and entomological studies of malaria transmission in Tibati, Adamawa region of Cameroon 6 years following the introduction of long-lasting insecticide nets.
Parasit Vectors
May 2021
Article Synopsis
- - Malaria is a significant public health issue in Cameroon, necessitating an understanding of local conditions for effective control measures; this research presents findings from Tibati, an area affected by seasonal malaria transmission, six years after long-lasting insecticidal bed nets were introduced.
- - Cross-sectional studies conducted in 2015 and 2017 involved blood samples from both symptomatic and asymptomatic individuals, along with adult mosquito collections, to assess the prevalence of Plasmodium species and identify infected mosquitoes through molecular methods.
- - The study revealed a 55% overall malaria prevalence, primarily caused by Plasmodium falciparum, with higher rates found in asymptomatic carriers; mosquito collections identified several species with a small percentage infected, highlighting the