TNF- Inhibitory Activity of Brazilian Plants and Anti-Inflammatory Effect of in an Acute Arthritis Model.

species, popularly named "barbatimão," are traditionally used in Brazil as anti-inflammatory agents. This study aimed to investigate the effect of barbatimão and 11 other species on the production of tumor necrosis factor-alpha (TNF-) in lipopolysaccharide- (LPS-) stimulated THP-1 cells, as well as their anti-arthritis activity. The extracts of , , , and promoted a concentration-dependent inhibition of TNF-.