To describe how 17β-estradiol (E2) influence in the monocyte/macrophage response induced by in models of murine peritoneal macrophages (MPMs) and human peripheral blood monocytes (HPBM). MPMs (2 x 10/ml) were isolated from sham (n=3) and ovariectomized (OVX) females (n = 3) and males (n = 3) after induction by thioglycolate. The MPMs obtained from OVX females and males were treated for 24 hours with 17β-estradiol (E2) (10 M), and after that, inoculation with was carried out for 6 hours.
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